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Weekly Brief | DeSci track vision and ecological overview
Cabin VC
特邀专栏作者
2022-12-28 04:12
This article is about 1448 words, reading the full article takes about 3 minutes
DeSci (Decentralized Science), as a relatively new concept, advocates the use of Web3 tools to fund, create, review, credit, store and disseminate scientific knowledge fairly and equally. At present, DeSci projects are mainly explored in the form of DAO.


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DeSci track vision and ecological overview


DeSci (Decentralized Science) is one of the relatively new concepts that have received attention in Gitcoin's latest round of donations.

DeSci's philosophy is that "scientific knowledge should be accepted by everyone, and the process of scientific research should be transparent", advocating the production of "science" in the form of "Public Goods", using Web3 tools to fund, create, review, Credibility, storage and dissemination of scientific knowledge, including: unrestricted information and data sharing, decentralization of research funding, expansion of the scope of participants in scientific activities, etc.

In the scientific research ecosystem envisioned by DeSci, scientists can be incentivized to share their research and work results openly, allowing anyone to access and contribute to research, and use more diverse funding sources, such as DAO, quadratic financing (Quadratic Funding), crowdfunding, etc., and provide more types of incentives.


Key questions in science comparing DeSci to the existing scientific environment include but are not limited to:

  • From an objective point of view, DeSci can be understood as a way of using Web3 technologies and tools to improve interdisciplinary science. The specific application scenarios that can be referred to are:


  • NFT can incentivize the community to share, simultaneously review and manage different types of information;

  • Blockchain technology can optimize the current review mechanism and avoid interference with science;

  • Smart contracts can be adjusted directly between authors and peer reviewers and distribute asset rewards;


  • Aligning blockchain-based public good funding models by establishing platforms and protocols dedicated to science;


Use the DeFi protocol to create long-term funds for sustainable innovation and development for scientists, etc.


Most importantly, the behavioral incentive mechanism enables the redistribution of resources in the entire ecology, so that everyone can get what they need and maximize the utilization of each resource. This is the key to the sustainable operation of the DeSci ecosystem.


After being supported and promoted by the head organization of Web3, there are more than 200 DeSci projects. Its ecological panorama development is still in the early stage, but there are many projects supported by the organization, and the number of projects is developing rapidly:


The main categories in the DeSci ecosystem are: DAOs / IP-NFTs (Intellectual Property NFTs) / DeSci Publishing / Decentralized Biosciences / DeSci Financing and Charity / Storage and Archiving, etc.


Looking at various categories, the biomedical category has attracted more attention in the direction of DeSci, and the income and profit margins of traditional biomedicine have brought more imagination. Recently, Molecule, a decentralized medical research project financing platform, received US$13 million in seed round financing, which is a representative project in the DeSci ecosystem.


Molecule is a biotech research fundraising platform and a decentralized biotech underlying protocol, which includes ideating IP NFTs, IP-related NFTs (drug or research-based IP), and launching the VitaDAO community to fund longevity Research, and reached a cooperation with Pfizer this year.


There are many DAO projects in the current DeSci ecosystem, which are still in the exploratory stage. Its goal is always to use DAO and other Web3 technologies as tools to form a relatively open community, and to unite communities in the same field to build a larger vision.


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Primary market investment dynamics


There were 15 investment and financing incidents announced last week, and the largest number of financing occurred in the NFT track, with a total of 6. The largest financing last week came from Web3 company Utopia Group, which completed 10 million euros (about 10.64 million U.S. dollars). Asterius VC led the investment and will provide consulting service support for its first NFT series Utopia Avatars; in addition, the NFT platform Revel completed a $7.8 million seed round of financing, led by Dragonfly Capital;



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